Opportunity Information: Apply for HHS 2021 ACF ACYF AP 1928

The Personal Responsibility Education Program Innovative Strategies (PREIS) opportunity is a discretionary federal funding program run by the U.S. Department of Health and Human Services, Administration for Children and Families (ACF), specifically the Administration on Children, Youth and Families (ACYF) and its Family and Youth Services Bureau (FYSB). Funding is provided through cooperative agreements, which means the federal government is not just issuing a grant and stepping back, but is expected to play an active partner role during the project. In practice, that “substantial involvement” can include ongoing coordination beyond normal reporting, such as regular conference calls, federal input on key project elements, and site visits.

The main goal of PREIS is to support projects that both implement an innovative adolescent pregnancy prevention strategy and test that strategy through a rigorous, well-designed evaluation. The emphasis is not only on delivering services, but on building credible evidence about what works, for whom, and under what conditions. Applicants are expected to propose approaches that go beyond standard programming and then pair those approaches with strong evaluation methods that can demonstrate impact.

A core priority of the program is reaching youth who are considered high-risk, vulnerable, and culturally under-represented. The opportunity highlights several examples of intended populations, including (but not limited to) youth in foster care, youth experiencing homelessness, youth living with HIV/AIDS, victims of human trafficking, pregnant women under age 21 and their partners, parenting mothers under age 21 and their partners, and youth living in communities with high adolescent birth rates. In other words, the funding is aimed at programs that are designed for groups who often face higher barriers to health education, stability, and consistent support systems.

Programmatically, funded projects must align with the Personal Responsibility Education Program (PREP) model requirements. That includes two major content expectations. First, programs must educate adolescents about both abstinence and contraception as methods for preventing pregnancy and sexually transmitted infections, including HIV/AIDS. Second, programs must include at least three topics from six adulthood preparation subject areas: healthy relationships, adolescent development, financial literacy, parent-child communication, educational and career success, and healthy life skills. This structure makes the program broader than sexual health instruction alone, pushing grantees to address practical knowledge and skills that support longer-term well-being and responsible decision-making.

Evaluation is a central, non-negotiable component of PREIS. Successful applicants are expected to carry out rigorous impact evaluations led by third-party, independent evaluators, reinforcing objectivity and methodological strength. The announcement identifies randomized controlled trials and quasi-experimental designs as acceptable approaches. Both require a clear comparison strategy, meaning participants are assigned or designated to either a treatment group that receives the program or a control/comparison group that does not (or receives an alternative condition). The clear intent is to generate defensible evidence of program effects rather than relying on informal feedback or pre-post changes without a comparison group.

In terms of basic award details, the funding opportunity number is HHS-2021-ACF-ACYF-AP-1928, listed under CFDA 93.092, with an activity focus in income security and social services. The anticipated maximum award amount is $900,000, and the agency expected to make about 12 awards. Eligibility is broad and includes multiple levels of government (state, county, city/township, special districts), independent school districts, public and private institutions of higher education, federally recognized tribal governments and other tribal organizations, public housing authorities/Indian housing authorities, nonprofit organizations (including those with or without 501(c)(3) status, as specified), for-profit organizations (other than small businesses), and small businesses. The posting date was June 15, 2021, with an original application deadline of July 26, 2021, and electronic submissions were required by 11:59 p.m. Eastern Time on the due date.

Overall, PREIS is designed for applicants that can do two things well at the same time: deliver high-quality, culturally responsive pregnancy prevention and youth development programming for populations with elevated needs, and execute a serious, independent evaluation capable of producing strong evidence about outcomes. The cooperative agreement structure also signals that funded organizations should be prepared for an active, ongoing relationship with ACF/ACYF/FYSB throughout the life of the project.

  • The Department of Health and Human Services, Administration for Children Families - ACYF/FYSB in the income security and social services sector is offering a public funding opportunity titled "Personal Responsibility Education Program Innovative Strategies (PREIS)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.092.
  • This funding opportunity was created on Jun 15, 2021.
  • Applicants must submit their applications by Jul 26, 2021 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $900,000.00 in funding.
  • The number of recipients for this funding is limited to 12 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses.
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