Opportunity Information: Apply for RFA NS 24 014
The NIH Blueprint and BRAIN Initiative Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (BP BRAIN-ENDURE) is a National Institutes of Health (NIH) Research Education Program (R25) funding opportunity designed to strengthen the neuroscience training pipeline by supporting undergraduate research education programs that help students from diverse backgrounds, especially those underrepresented in biomedical, behavioral, and clinical research, prepare for entry into Ph.D. programs in the neurosciences. The overall intent is workforce development: building sustained, structured pathways that increase the number of well-prepared trainees from underrepresented groups who move from undergraduate education into rigorous doctoral-level neuroscience research training. This particular R25 is listed as "Clinical Trial Not Allowed," meaning supported activities must be educational and research training oriented rather than proposing clinical trial studies.
The program emphasizes fully integrated, high-quality educational experiences rather than isolated activities. Applicants are expected to build creative and coordinated programs that center on three main components: courses for skills development, hands-on research experiences, and robust mentoring. In practice, this means undergraduate participants should receive targeted training that builds research readiness (for example, quantitative and analytical skills, responsible conduct of research, scientific communication, and other foundational competencies), paired with meaningful research placements and sustained mentorship that supports both scientific growth and long-term career planning. The expectation is that these elements work together as one coherent program that moves students toward competitiveness for neuroscience Ph.D. admissions and future research careers.
A defining feature of BP BRAIN-ENDURE is the requirement for collaborative partnerships that bridge different types of institutions. Each funded program must be built around a partnership that includes: (a) one or more institutions with a historic and current mission to educate students from populations underrepresented in biomedical research as defined by the National Science Foundation (NSF), or institutions with a strong, documented record of recruiting, training, graduating, and advancing such students into biomedical research trajectories; and (b) a research-intensive institution that has an established neuroscience or neuroscience-related program. The purpose of this structure is to connect student talent and supportive learning environments with high-intensity research infrastructure, neuroscience expertise, and doctoral training ecosystems, so that students can gain authentic research exposure, professional networks, and preparation aligned with Ph.D. expectations.
The populations highlighted as underrepresented (using NSF definitions referenced in the opportunity) include African Americans or Blacks, Hispanic or Latino Americans, American Indians, Alaska Natives, Native Hawaiians, U.S. Pacific Islanders, and persons with disabilities. Programs supported under this funding opportunity are expected to be intentional about recruitment, training design, and mentorship practices that address barriers to entry and persistence in neuroscience research, while also providing the academic and research experiences that make students stronger candidates for doctoral training.
Eligibility is broad in the sense that many organization types may apply, including public and private institutions of higher education, nonprofits (with or without 501(c)(3) status), for-profit organizations (other than small businesses), small businesses, and various governmental entities (state, county, city/township, special districts, independent school districts), as well as tribal governments and tribal organizations. The opportunity also explicitly calls out relevant institution categories that often serve underrepresented populations, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with eligible federal agencies and faith-based or community-based organizations. At the same time, there are clear restrictions on foreign involvement: non-U.S. (foreign) entities and foreign institutions are not eligible to apply, non-domestic components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed.
From a logistics standpoint, the opportunity is issued by NIH under Funding Opportunity Number RFA-NS-24-014, categorized as a discretionary grant in the education-related activity area. Multiple NIH CFDA numbers are associated with the announcement (reflecting participation across NIH components). The original closing date listed is February 10, 2025, and the funding record notes the opportunity was created on July 21, 2023. While the excerpt does not provide an award ceiling or the expected number of awards, the program is described as making institutional awards, meaning the funding is intended to support the development and operation of the partnered research education program rather than providing individual fellowships alone.
Overall, BP BRAIN-ENDURE is aimed at building durable, partnership-based undergraduate research education programs in neuroscience that combine skill-building coursework, real research immersion, and strong mentoring to help more underrepresented students successfully transition into neuroscience Ph.D. programs and, ultimately, into the biomedical research workforce.Apply for RFA NS 24 014
- The National Institutes of Health in the education, environment, health, income security and social services sector is offering a public funding opportunity titled "NIH Blueprint and BRAIN Initiative Program for Enhancing Neuroscience Diversity through Undergraduate Research Education Experiences (BP BRAIN-ENDURE) (R25 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.173, 93.213, 93.242, 93.273, 93.279, 93.286, 93.853, 93.865, 93.866, 93.867.
- This funding opportunity was created on 2023-07-21.
- Applicants must submit their applications by 2025-02-10. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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| Funding Opportunity |
|---|
| Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional) Apply for PAR 23 293 Funding Number: PAR 23 293 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ethical, Legal and Social Implications (ELSI) Exploratory/Developmental Research Grant (R21 Clinical Trial Optional) Apply for PAR 23 294 Funding Number: PAR 23 294 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $275,000 |
| Ethical, Legal and Social Implications (ELSI) Small Research Grant (R03 Clinical Trial Optional) Apply for PAR 23 295 Funding Number: PAR 23 295 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $50,000 |
| BRAIN Initiative: Marmoset Colonies for Neuroscience Research (U24 Clinical Trials Not Allowed) Apply for RFA MH 25 115 Funding Number: RFA MH 25 115 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Marmoset Coordination Center (U24 Clinical Trials Not Allowed) Apply for RFA MH 25 116 Funding Number: RFA MH 25 116 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Blueprint and BRAIN Initiative Diversity Specialized Predoctoral to Postdoctoral Advancement in Neuroscience (D-SPAN) Award (F99/K00 Clinical Trial Not Allowed) Apply for RFA NS 24 030 Funding Number: RFA NS 24 030 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Basic Experimental Studies with Humans Required) Apply for PA 24 186 Funding Number: PA 24 186 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Quantitative Research Development Award (Parent K25 Independent Basic Experimental Studies with Humans Required) Apply for PA 24 192 Funding Number: PA 24 192 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required) Apply for PA 24 181 Funding Number: PA 24 181 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Basic Experimental Studies with Humans Required) Apply for PA 24 183 Funding Number: PA 24 183 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Research Scientist Development Award (Parent K01 Independent Basic Experimental Studies with Humans Required) Apply for PA 24 177 Funding Number: PA 24 177 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Pathway to Independence Award (Parent K99/R00 Independent Basic Experimental Studies with Humans Required) Apply for PA 24 195 Funding Number: PA 24 195 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Small Business Transition Grant for New Entrepreneurs (R41/R42 Clinical Trial Not Allowed) Apply for PAR 24 133 Funding Number: PAR 24 133 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| PHS 2024-2 Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Required) Apply for PA 24 248 Funding Number: PA 24 248 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Maximizing Opportunities for Scientific and Academic Independent Careers (MOSAIC) Postdoctoral Career Transition Award to Promote Diversity (K99/R00 - Independent Basic Experimental Studies with Humans Required (BESH)) Apply for PAR 24 227 Funding Number: PAR 24 227 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Human Brain Single-cell Genomics Explorer (U24 - Clinical Trial Not Allowed) Apply for RFA NS 24 038 Funding Number: RFA NS 24 038 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: $1,000,000 |
| Environmental Health Disparities Centers (P50) Clinical Trial Optional Apply for RFA MD 24 010 Funding Number: RFA MD 24 010 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed) Apply for PAR 25 233 Funding Number: PAR 25 233 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Dissemination and Implementation Research in Health (R21 Clinical Trial Optional) Apply for PAR 25 143 Funding Number: PAR 25 143 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32) Apply for PA 25 168 Funding Number: PA 25 168 Agency: National Institutes of Health Category: Education, Environment, Health, Income Security and Social Services Funding Amount: Case Dependent |
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