Molecular Transducers of Physical Activity Consortium Coordinating Center (CCC) (U24) | RFA RM 15 014

Opportunity Information: Apply for RFA RM 15 014

The Molecular Transducers of Physical Activity Consortium Coordinating Center (CCC) (U24) opportunity (RFA-RM-15-014) is a National Institutes of Health (NIH) cooperative agreement designed to support a single Coordinating Center for the Molecular Transducers of Physical Activity Consortium (MoTrPAC). MoTrPAC is a Common Fund effort focused on understanding the molecular changes in the body that are triggered by physical activity. Rather than funding another individual research project site, this award is meant to fund the central hub that keeps a large, multi-site consortium operating as one cohesive program, with consistent protocols, shared standards, and coordinated outputs.

The core purpose of the CCC is overall coordination and day-to-day operational management of the MoTrPAC consortium. That includes organizing and supporting consortium governance, communication, and planning across participating institutions and study teams. A major responsibility is managing the development, harmonization, and implementation of study protocols, so that data and biospecimens collected across sites are comparable and can be analyzed together. The CCC is also expected to coordinate logistics for the collection, management, and distribution of both data and biological samples generated during the project. In practical terms, this typically means overseeing standardized operating procedures, timelines, data flow, quality control processes, and systems that ensure materials and datasets move to the right places securely and efficiently.

Another major deliverable is helping create a lasting research resource for future investigators. This implies building the infrastructure and processes needed for long-term usability of consortium outputs, such as well-annotated datasets, curated metadata, and responsibly managed biospecimen inventories, along with clear rules for access and sharing. The intent is not just to run the studies while the award is active, but to ensure that what the consortium produces can be reused later by the broader scientific community, consistent with NIH policies and the NIH Grants Policy Statement.

This funding opportunity is categorized as discretionary funding, using a cooperative agreement mechanism (U24). A cooperative agreement means NIH is expected to have substantial involvement in the project, so the CCC will operate in close partnership with NIH program leadership and the rest of the consortium. The activity category is health, and the associated CFDA number is 93.310. NIH anticipated making one award under this announcement, emphasizing that the CCC is intended to be a single central coordinating entity rather than multiple competing centers. The announcement was created on October 8, 2015, with an original closing date of March 18, 2016. The award ceiling is not specified in the provided source.

Eligibility is broad across many U.S.-based organization types. Eligible applicants include various levels of government (state, county, city or township, special district), independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, federally recognized Native American tribal governments, and Native American tribal organizations that are not federally recognized tribal governments. Both nonprofit organizations (with or without 501(c)(3) status) and for-profit organizations (other than small businesses), as well as small businesses, may apply. The opportunity also explicitly highlights additional eligible applicant categories such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, Indian/Native American tribal governments other than federally recognized, and U.S. territories or possessions.

Foreign participation is limited. Non-domestic (non-U.S.) entities are not eligible to apply as applicants, and non-domestic components of U.S. organizations are not eligible to apply. However, foreign components as defined in the NIH Grants Policy Statement are allowed, meaning certain discrete parts of the work can be performed outside the U.S. under the rules NIH sets for foreign components, even though the applicant organization itself must be domestic and the overall award remains U.S.-based.

In short, this FOA supports the central coordinating infrastructure for MoTrPAC, with responsibilities spanning consortium-wide coordination, protocol and operations management, data and biospecimen logistics, and building a durable scientific resource that extends the impact of the consortium beyond the funded project period.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Molecular Transducers of Physical Activity Consortium Coordinating Center (CCC) (U24)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.310.
• This funding opportunity was created on 2015-10-08.
• Applicants must submit their applications by 2016-03-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• The number of recipients for this funding is limited to 1 candidate(s).
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA RM 15 014

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