Opportunity Information: Apply for PA 18 575
PHS 2018-02 is an omnibus Small Business Technology Transfer (STTR) grant solicitation led by the National Institutes of Health (NIH), and it also sits within the broader NIH/CDC/FDA SBIR/STTR ecosystem. The core purpose is to fund early-stage, high-impact research and development projects where a U.S. small business formally collaborates with a nonprofit research institution to move innovative science toward practical products, tools, or services that align with the missions of participating NIH awarding components. This is a "Parent" STTR opportunity, meaning it is designed to be broadly applicable across many biomedical and public health topic areas rather than being limited to a single disease, technology, or institute-specific initiative.
The funding mechanism is the STTR program using the R41/R42 activity codes. In practical terms, this typically maps to a phased pathway: Phase I (R41) supports feasibility and proof-of-concept work, while Phase II (R42) supports more advanced R and D aimed at developing the technology further, reducing technical risk, and positioning it for later-stage commercialization or deployment. Applications are expected to fit within the research topics and guidance referenced in the PHS 2018-2 SBIR/STTR Program Descriptions and Research Topics for NIH, which applicants use to align their proposed work with the priorities and interests of the NIH components participating under this umbrella.
A key restriction in this particular announcement is that clinical trials are not allowed. That means applicants must structure their aims so they do not propose a study that meets NIH's definition of a clinical trial (for example, prospective assignment of human participants to an intervention to evaluate effects on health-related outcomes). Projects can still involve many forms of non-clinical development and testing that are common in biomedical innovation, such as laboratory validation, benchtop prototyping, assay development, preclinical studies, computational modeling, device engineering, software development, data infrastructure work, or other R and D activities, as long as they do not cross into clinical trial territory. Applicants who do need to run a clinical trial would generally have to look for a different FOA explicitly allowing or soliciting clinical trials.
Eligibility is tightly focused on U.S. small business concerns. The applicant organization must qualify as a small business under applicable STTR rules and must be based in the United States. Foreign institutions are not eligible to apply, and non-U.S. components of U.S. organizations are also not eligible to serve as the applicant entity. However, foreign components, as defined in the NIH Grants Policy Statement, may be allowed in some cases, which can matter when a portion of the work, expertise, or resources is legitimately located outside the U.S. Even then, applicants would need to follow NIH policy and clearly justify why a foreign component is necessary and how it benefits the project in a way that cannot be readily achieved domestically.
From an administrative perspective, the opportunity is categorized as discretionary grant funding. The funding activity spans multiple public service domains (including health, environment, food and nutrition, education, and social services), reflecting how NIH-supported innovations can cut across clinical medicine, population health, research tools, and enabling technologies. The listing includes a large set of CFDA numbers (now commonly referred to under Assistance Listings), which signals that many NIH institutes and centers may make awards under their relevant authorities, depending on the topic alignment and application quality.
The opportunity number is PA 18 575, with an original closing date listed as 2019-04-05, and the creation date shown as 2018-01-16. While the excerpt does not specify an award ceiling or the expected number of awards, STTR awards are typically made competitively based on scientific and technical merit, programmatic fit with the participating NIH component, and the credibility of the project plan for advancing the technology toward commercialization. In line with the STTR program’s purpose, strong applications usually show a clear technical need, a convincing innovation story, a feasible and well-structured work plan for the phase being requested, and a realistic path to downstream use, adoption, or commercialization, all while maintaining the required collaboration between the small business and the partner research institution.
In short, this FOA is a broad NIH parent solicitation that funds U.S. small businesses working with research partners to develop biomedical and health-related technologies through the STTR R41/R42 pathway, with the explicit condition that proposed research must not include clinical trials and with eligibility limits that generally exclude non-U.S. applicant entities while allowing certain foreign components under NIH policy when appropriately justified.Apply for PA 18 575
- The National Institutes of Health in the education, environment, food and nutrition, health, income security and social services sector is offering a public funding opportunity titled "PHS 2018-02 Omnibus Solicitation of the NIH, CDC, and FDA for Small Business Technology Transfer Grant Applications (Parent STTR [R41/R42] Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.173, 93.213, 93.233, 93.242, 93.273, 93.279, 93.286, 93.307, 93.350, 93.351, 93.361, 93.393, 93.394, 93.395, 93.396, 93.399, 93.837, 93.838, 93.839, 93.840, 93.846, 93.847, 93.853, 93.855, 93.856, 93.859, 93.865, 93.866, 93.867, 93.879.
- This funding opportunity was created on 2018-01-16.
- Applicants must submit their applications by 2019-04-05. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 18 575) also looked into and applied for these:
| Funding Opportunity |
|---|
| Research Supplements to Promote Diversity in Health-Related Research (Admin Supp - Clinical Trial Not Allowed) Apply for PA 18 586 Funding Number: PA 18 586 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp - Clinical Trial Optional) Apply for PA 18 591 Funding Number: PA 18 591 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Successor-in-Interest (Type 6 Parent Clinical Trial Optional) Apply for PA 18 589 Funding Number: PA 18 589 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Change of Grantee Organization (Type 7 Parent Clinical Trial Optional) Apply for PA 18 590 Funding Number: PA 18 590 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Research Supplements to Promote Re-Entry into Biomedical and Behavioral Research Careers (Admin Supp - Clinical Trial Not Allowed ) Apply for PA 18 592 Funding Number: PA 18 592 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| NIH Support for Conferences and Scientific Meetings (Parent R13 Clinical Trial Not Allowed) Apply for PA 18 648 Funding Number: PA 18 648 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplement for Research on Sex/Gender Influences (Admin Supp - Clinical Trial Optional) Apply for PA 18 658 Funding Number: PA 18 658 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship to Promote Diversity in Health-Related Research (Parent F31) Apply for PA 18 666 Funding Number: PA 18 666 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 18 668 Funding Number: PA 18 668 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Predoctoral Fellowship (Parent F31) Apply for PA 18 671 Funding Number: PA 18 671 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (Parent F32) Apply for PA 18 670 Funding Number: PA 18 670 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Ruth L. Kirschstein National Research Service Award (NRSA)Individual Fellowship for Students at Institutions Without NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30) Apply for PA 18 673 Funding Number: PA 18 673 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Lasker Clinical Research Scholars Program (Si2/R00 Clinical Trial Optional) Apply for PAR 18 740 Funding Number: PAR 18 740 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Administrative Supplements for Research on Dietary Supplements (Admin. Supp.- Clinical Trial Not Allowed) Apply for PA 18 817 Funding Number: PA 18 817 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: $100,000 |
| Research Project Grant (Parent R01 Clinical Trial Not Allowed) Apply for PA 19 056 Funding Number: PA 19 056 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Required) Apply for PA 19 116 Funding Number: PA 19 116 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Clinical Scientist Research Career Development Award (Parent K08 Independent Clinical Trial Not Allowed) Apply for PA 19 117 Funding Number: PA 19 117 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Quantitative Research Development Award (Parent K25 - Independent Clinical Trial Required) Apply for PA 19 125 Funding Number: PA 19 125 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Not Allowed) Apply for PA 19 119 Funding Number: PA 19 119 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Mentored Patient-Oriented Research Career Development Award (Parent K23 Independent Clinical Trial Required) Apply for PA 19 118 Funding Number: PA 19 118 Agency: National Institutes of Health Category: Education, Environment, Food and Nutrition, Health, Income Security and Social Services Funding Amount: Case Dependent |
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